Description

1H-1,2,4-Triazole-1-Carbonylchloride(9Ci) is a versatile and highly reactive acyl chloride derivative of the 1,2,4-triazole heterocycle, serving as a critical building block for the synthesis of complex molecules. Its primary value lies in its ability to efficiently introduce the 1,2,4-triazole-1-carbonyl moiety, a key functional group in advanced chemical synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create active ingredients, intermediates, and novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing triazole-based pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators that leverage the triazole ring system.
• Peptide & Protein Research: Acts as a coupling reagent or protecting group agent in peptide synthesis and bioconjugation chemistry.
• Material Science: Employed in the creation of specialty polymers, ligands for catalysis, and advanced organic frameworks.
• Chemical Research & Development: A fundamental reagent for medicinal chemistry and process chemistry in developing new chemical entities.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke intermediates.

Basic Information

Product Name	1H-1,2,4-Triazole-1-Carbonylchloride(9Ci)
CAS No.	852324-06-2
Molecular Formula	C3H2ClN3O
Molecular Weight	131.52 g/mol
Synonyms	1,2,4-Triazole-1-carbonyl chloride; 1H-1,2,4-Triazole-1-carbonyl chloride; 1-Carbonylchloride-1,2,4-triazole; Triazole-1-carbonyl chloride; 1,2,4-Triazole-1-carboxylic acid chloride; 852324-06-2; 1,2,4-Triazol-1-ylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-1,2,4-Triazole-1-Carbonylchloride(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive analytical data, including HPLC purity, NMR, and IR spectroscopy for identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support custom purity requirements to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.