Description

Amuvatinib is a potent and selective small-molecule inhibitor targeting specific receptor tyrosine kinases. This compound is of significant interest in advanced pharmaceutical research and development due to its targeted mechanism of action. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in oncology and related therapeutic areas.

Application

• Pharmaceutical Research & Development: A key intermediate or active pharmaceutical ingredient (API) in the development of novel targeted cancer therapies.
• Biochemical Research: Used as a selective inhibitor in kinase assay studies to investigate cellular signaling pathways and mechanisms of disease.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicology profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratory settings.

Basic Information

Product Name	Amuvatinib
CAS No.	850879-09-3
Molecular Formula	C₂₃H₂₅ClFN₅O₂
Molecular Weight	457.93 g/mol
Synonyms	MP-470; MGCD-265; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine; UNII-3V3L5WFD0J; MGCD265; MP 470; Amuvatinib (MP470); 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-
EINECS	Contact for details

Quality Control

Our Amuvatinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.