Description

2-Fluoro-3-Methoxybenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2-fluoro-3-methoxybenzoyl moiety into target molecules, enabling the development of compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for creating active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and methoxy substituents can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional side chains into polymers, altering their thermal, mechanical, or solubility characteristics for specialty plastics and coatings.
• Peptide & Protein Research: Can be used as an acylating agent in biochemical research for modifying amino acids or peptides.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-3-Methoxybenzoyl Chloride
CAS No.	850563-45-0
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	2-Fluoro-3-methoxybenzoyl chloride; 3-Methoxy-2-fluorobenzoyl chloride; 2-Fluoro-m-anisoyl chloride; 850563-45-0; Benzoyl chloride, 2-fluoro-3-methoxy-; o-Fluoro-m-methoxybenzoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methoxybenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.