Description

5-Bromobenzo[B]Thiophene-3-Carbonyl Chloride is a high-purity, reactive chemical building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex heterocyclic molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used to develop novel herbicides, fungicides, or insecticides with unique modes of action based on the benzothiophene scaffold.
• Material Science: Serves as a monomer or functionalization agent for creating specialized polymers or organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological processes.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	5-Bromobenzo[B]Thiophene-3-Carbonyl Chloride
CAS No.	850374-99-1
Molecular Formula	C9H4BrClOS
Molecular Weight	275.55 g/mol
Synonyms	5-Bromobenzo[b]thiophene-3-carbonyl chloride; 5-Bromo-1-benzothiophene-3-carbonyl chloride; 5-Bromobenzo[b]thiophene-3-carboxylic acid chloride; 3-Chlorocarbonyl-5-bromobenzo[b]thiophene; 5-Bromo-benzo[b]thiophene-3-carbonyl chloride; 850374-99-1; 5-Bromobenzo(b)thiophene-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Bromobenzo[B]Thiophene-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.