Description

2,5-Difluoro-4-Methoxybenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of a substituted benzoyl moiety. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a difluoromethoxybenzoyl scaffold.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the specific substitution pattern influences biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating complex organic molecules used in electronic displays and lighting.
• Polymer Chemistry: Can be employed as a monomer or modifier in the production of specialty polymers with unique thermal or chemical properties.
• Peptide & Protein Modification: Utilized as an acylating agent for modifying amino acids or biomolecules in biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,5-Difluoro-4-Methoxybenzoyl Chloride
CAS No.	849632-70-8
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	4-Methoxy-2,5-difluorobenzoyl chloride; 2,5-Difluoro-4-methoxybenzoic acid chloride; 2,5-Difluoro-p-anisoyl chloride; 849632-70-8; Benzoyl chloride, 2,5-difluoro-4-methoxy-; p-Methoxy-2,5-difluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-Methoxybenzoyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.