Description

2,3-Difluoro-4-Methoxybenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative. This compound serves as a critical pharmaceutical intermediate and versatile building block for synthesizing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors to introduce the difluoromethoxybenzoyl moiety into target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro-methoxy group enhances biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional side chains into polymers to alter physical properties like solubility, thermal stability, and refractive index.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom chemical synthesis and scale-up services for specialized client projects.
• Research & Development: Essential tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Item	Details
Product Name	2,3-Difluoro-4-Methoxybenzoyl Chloride
CAS No.	849632-69-5
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	4-Methoxy-2,3-difluorobenzoyl chloride; 2,3-Difluoro-4-methoxybenzoic acid chloride; 2,3-Difluoro-p-anisoyl chloride; 849632-69-5; Benzoyl chloride, 2,3-difluoro-4-methoxy-; 2,3-Difluoro-4-methoxybenzoylchloride; 2,3-Difluoro-4-methoxy-benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxybenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.