Description

5-(3,4-Dimethyl-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride is a high-value, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic frameworks, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is critically needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials and specialty polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	5-(3,4-Dimethyl-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride
CAS No.	848436-24-8
Molecular Formula	C₁₇H₁₁ClF₃N₃O
Molecular Weight	365.74 g/mol
Synonyms	5-(3,4-Dimethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 7-Trifluoromethyl-5-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; Pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 5-(3,4-dimethylphenyl)-7-(trifluoromethyl)-; 848436-24-8; CAS 848436-24-8
EINECS	Contact for details

Quality Control

Our production of 5-(3,4-Dimethyl-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.