Description

5-(4-Fluoro-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride is a high-value, multifunctional chemical building block designed for advanced synthesis. This compound is critical for research and development in pharmaceutical and agrochemical sectors, where its unique heterocyclic structure enables the creation of novel active ingredients. It is primarily sought by fine chemical manufacturers, contract research organizations (CROs), and academic institutions engaged in developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials and specialty polymers.
• Chemical Biology: Employed as a probe or linker in the design of molecular tools for studying biological pathways and protein interactions.
• Custom Synthesis: A versatile starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific R&D projects.

Basic Information

Product Name	5-(4-Fluoro-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride
CAS No.	848422-44-6
Molecular Formula	C14H6ClF4N3O
Molecular Weight	343.66 g/mol
Synonyms	5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 848422-44-6; Pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 5-(4-fluorophenyl)-7-(trifluoromethyl)-; 5-(p-Fluorophenyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluoro-Phenyl)-7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.