Description

Azd0865 (Linaprazan) is a potent and selective potassium-competitive acid blocker (P-CAB) pharmaceutical intermediate. This compound is of significant interest for its role in the development of novel treatments for acid-related gastrointestinal disorders, offering a differentiated mechanism of action compared to traditional proton pump inhibitors. It is primarily required by pharmaceutical R&D departments, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences sector. CAS NO 847574-05-4.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical intermediate in the production of the P-CAB drug Linaprazan.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies to investigate new formulations and therapeutic applications for gastric acid suppression.
• Reference Standard: Employed as a high-purity standard in analytical method development, validation, and quality control testing within pharmaceutical laboratories.
• Mechanistic Studies: Utilized in biochemical and pharmacological research to study potassium-competitive acid blockade and its effects on gastric proton pumps.
• Process Chemistry Optimization: Acts as a key building block for chemists developing and scaling up efficient, cost-effective synthetic routes.

Basic Information

Product Name	Azd0865 (Linaprazan)
CAS No.	847574-05-4
Molecular Formula	C17H16F3N3O2S
Molecular Weight	383.39 g/mol
Synonyms	Linaprazan; AZD0865; 2-[(4-Fluorophenyl)methylsulfinyl]-N-[1-(2-methoxyethyl)-4-(trifluoromethyl)-1H-imidazol-5-yl]acetamide; UNII-6Q5H5I16QN; AZD-0865
EINECS	Contact for details

Quality Control

Our Azd0865 (Linaprazan) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) with detailed batch-specific results are provided to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.