Description

1-Biphenylenecarbonyl Chloride is a specialized aromatic acid chloride derivative, serving as a high-value synthetic intermediate in advanced organic synthesis. Its core value proposition lies in enabling the efficient introduction of the rigid, planar biphenylene moiety into target molecules, which is critical for modulating electronic and structural properties. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring specific planar aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the biphenylene group can enhance binding affinity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in organometallic chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Advanced Materials Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the biphenylene unit contributes to charge transport and thermal stability.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	1-Biphenylenecarbonyl Chloride
CAS No.	844891-07-2
Molecular Formula	C13H7ClO
Molecular Weight	214.65 g/mol
Synonyms	Biphenylene-1-carbonyl chloride; Biphenylene-1-carboxylic acid chloride; 1-Carboxybiphenylene chloride; Biphenylene carbonyl chloride; Biphenylene carboxylic acid chloride; 1-Biphenylenecarboxylic acid chloride; Biphenylene-1-COCl
EINECS	Contact for details

Quality Control

Our 1-Biphenylenecarbonyl Chloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods including HPLC, NMR, and IR spectroscopy. We are committed to meeting the stringent requirements of research and development, and specifications can be aligned with client-specific needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.