Description

3,4',5-Trifluorobenzhydrol is a versatile fluorinated organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its benzhydrol core structure, which serves as a key building block for constructing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty agrochemicals where the introduction of fluorine atoms is critical for modulating biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where fluorination enhances lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the synthesis of charge-transport materials and semiconductors for OLEDs and other electronic devices.
• Cross-Coupling Reactions: Acts as a substrate or precursor in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research & Development: A valuable building block for exploring new fluorination methodologies and creating compound libraries for screening.

Basic Information

Product Name	3,4',5-Trifluorobenzhydrol
CAS No.	844856-31-1
Molecular Formula	C13H9F3O
Molecular Weight	238.21 g/mol
Synonyms	[3,4',5-Trifluoro[1,1'-biphenyl]-4-yl]methanol; (3,4',5-Trifluorobiphenyl-4-yl)methanol; α-(3,4',5-Trifluorophenyl)benzenemethanol; 1-(3,4',5-Trifluoro[1,1'-biphenyl]-4-yl)methanol; Benzhydrol, 3,4',5-trifluoro-; 3,4',5-Trifluoro-4-(hydroxymethyl)biphenyl
EINECS	Contact for details

Quality Control

Our 3,4',5-Trifluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global customer base in research and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.