Description

3,3',5-Trifluorobenzhydrol is a high-value fluorinated benzhydrol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its primary commercial importance lies in its role as a versatile building block for the synthesis of complex, bioactive molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing new active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty polymers where the introduction of a trifluoromethyl-substituted diphenylmethanol scaffold is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated compounds used in electronic displays due to its influence on molecular polarity and alignment.
• Organic Light-Emitting Diodes (OLEDs): Acts as an intermediate for electron-transport materials and host compounds in OLED device fabrication.
• Specialty Polymer Monomer: Utilized in the synthesis of high-performance, fluorinated polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	3,3',5-Trifluorobenzhydrol
CAS No.	844683-66-5
Molecular Formula	C13H9F3O
Molecular Weight	238.21 g/mol
Synonyms	[3,3',5-Trifluorophenyl]phenylmethanol; α-(3,5-Difluorophenyl)-α-(3-fluorophenyl)methanol; 1,1-Bis(3-fluorophenyl)-1-methanol (asymmetric isomer); 3,3',5-Trifluorodiphenylmethanol; 3,3',5-Trifluorobenzhydryl alcohol; (3,3',5-Trifluorodiphenyl)methanol; Benzhydrol, 3,3',5-trifluoro-
EINECS	Contact for details

Quality Control

Our 3,3',5-Trifluorobenzhydrol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.