Description

3,4'-Dichloro-3'-Fluorobenzhydrol is a high-purity fluorinated and chlorinated benzhydrol derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate). Its unique halogenated structure makes it a valuable building block for synthesizing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its halogenated aromatic system contributes to bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals due to its rigid, substituted biphenyl-like core.
• Organic Synthesis Building Block: A versatile starting material for further functionalization, including oxidation to ketones or reactions at the benzylic alcohol group.

Basic Information

Product Name	3,4'-Dichloro-3'-Fluorobenzhydrol
CAS No.	844683-47-2
Molecular Formula	C13H9Cl2FO
Molecular Weight	275.11 g/mol
Synonyms	(3-Chloro-4-fluorophenyl)(2,4-dichlorophenyl)methanol; 1-(3-Chloro-4-fluorophenyl)-1-(2,4-dichlorophenyl)methanol; Benzhydrol, 3,4'-dichloro-3'-fluoro-; α-(3-Chloro-4-fluorophenyl)-2,4-dichlorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our 3,4'-Dichloro-3'-Fluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.