Description

4-Chloro-3,4'-Difluorobenzhydrol (CAS NO 844683-37-0) is a high-value fluorinated benzhydrol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both chloro and fluoro substituents, makes it an essential building block for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro motif enhances bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Polymer Chemistry: Intermediate for creating specialty polymers with enhanced chemical resistance and thermal stability.
• Organic Electronics: Utilized in the research and development of organic semiconductors and charge-transport materials.
• Chemical Research: A versatile scaffold in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	4-Chloro-3,4'-Difluorobenzhydrol
CAS No.	844683-37-0
Molecular Formula	C13H9ClF2O
Molecular Weight	254.66 g/mol
Synonyms	(4-Chloro-3-fluorophenyl)(4-fluorophenyl)methanol; 1-(4-Chloro-3-fluorophenyl)-1-(4-fluorophenyl)methanol; α-(4-Chloro-3-fluorophenyl)-4-fluorobenzyl alcohol; Benzhydrol, 4-chloro-3,4'-difluoro-; 4-Chloro-α-(4-fluorophenyl)-3-fluorobenzenemethanol
EINECS	Contact for details

Quality Control

Our 4-Chloro-3,4'-Difluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, prolonged exposure to air should be minimized.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.