Description

3-Fluoro-3'-Methylbenzhydrol is a high-purity fluorinated benzhydrol derivative, serving as a critical chiral intermediate in advanced organic synthesis. Its value lies in the precise molecular architecture provided by the fluorine and methyl substituents, which are essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorine atom enhances lipophilicity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Chiral Catalyst Ligand Synthesis: The benzhydrol scaffold can be modified to produce novel ligands for asymmetric catalysis.
• Polymer Science: Intermediate for specialty monomers that impart unique properties to high-performance polymers.
• Chemical Research: A versatile reagent for studying structure-activity relationships (SAR) in medicinal chemistry programs.

Basic Information

Product Name	3-Fluoro-3'-Methylbenzhydrol
CAS No.	844683-31-4
Molecular Formula	C14H13FO
Molecular Weight	216.25 g/mol
Synonyms	[3-Fluoro-3'-methylphenyl]phenylmethanol; (3-Fluoro-3-methylphenyl)(phenyl)methanol; α-(3-Fluorophenyl)-3-methylbenzenemethanol; Benzhydrol, 3-fluoro-3'-methyl-; 3-Fluoro-3'-methyl diphenylmethanol; 3-Fluoro-3'-methylbenzhydryl alcohol
EINECS	Contact for details

Quality Control

Our 3-Fluoro-3'-Methylbenzhydrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.