Description

3,5-Difluoro-3'-Methylbenzhydrol is a specialized fluorinated benzhydrol derivative, a key chiral intermediate in advanced organic synthesis. Its molecular structure, featuring strategically placed fluorine and methyl groups, makes it a valuable building block for creating complex molecules with tailored electronic and steric properties. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro motif enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a backbone for constructing sophisticated chiral ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for advanced materials, such as liquid crystals and polymers.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	3,5-Difluoro-3'-Methylbenzhydrol
CAS No.	842140-75-4
Molecular Formula	C15H12F2O
Molecular Weight	246.25 g/mol
Synonyms	[3,5-Difluorophenyl][3-methylphenyl]methanol; (3,5-Difluorophenyl)(3-methylphenyl)methanol; α-(3,5-Difluorophenyl)-3-methylbenzenemethanol; 1-(3,5-Difluorophenyl)-1-(3-methylphenyl)methanol; Benzhydrol, 3,5-difluoro-3'-methyl-; 842140-75-4
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-3'-Methylbenzhydrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.