Description

3-Chloro-5-Fluorobenzhydrol is a versatile fluorinated and chlorinated benzhydrol derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring both halogen substituents and a benzhydrol moiety, makes it highly valuable for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides that require halogenated aromatic structures.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Serves as a standard or starting material in method development and exploratory organic chemistry.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-Chloro-5-Fluorobenzhydrol
CAS No.	842140-65-2
Molecular Formula	C13H10ClFO
Molecular Weight	236.67 g/mol
Synonyms	(3-Chloro-5-fluorophenyl)(phenyl)methanol; α-(3-Chloro-5-fluorophenyl)benzenemethanol; Benzhydrol, 3-chloro-5-fluoro-; 3-Chloro-5-fluoro-α-phenylbenzenemethanol; 842140-65-2; (3-Chloro-5-fluorophenyl)-phenyl-methanol
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorobenzhydrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.