Description

4-(Cyclopropylamino)-5-Fluoro-1-β-L-Ribofuranosylpyrimidinone is a high-purity nucleoside analog intermediate of significant importance in modern pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of novel antiviral and anticancer agents, particularly within the field of modified nucleoside therapeutics. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of investigational antiviral drugs, including potential treatments for viral infections.
• Anticancer Agent Research: Serves as a building block for developing nucleoside-based chemotherapeutic candidates that target DNA/RNA synthesis.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate metabolic pathways and inhibition mechanisms.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Prodrug Development: Acts as a core structure for designing prodrugs aimed at improving bioavailability and targeted delivery.

Basic Information

Product Name	4-(Cyclopropylamino)-5-Fluoro-1-β-L-Ribofuranosylpyrimidinone
CAS No.	842119-99-7
Molecular Formula	C12H16FN3O5
Molecular Weight	301.27 g/mol
Synonyms	4-(Cyclopropylamino)-5-fluoro-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one; 5-Fluoro-4-(cyclopropylamino)-1-β-L-ribofuranosyl-2(1H)-pyrimidinone; β-L-Fd4C Intermediate; L-Nucleoside Analog Intermediate; 4-Amino-5-fluoro-1-β-L-ribofuranosyl-2(1H)-pyrimidinone, N-cyclopropyl-; 842119-99-7
EINECS	Contact for details

Quality Control

Our 4-(Cyclopropylamino)-5-Fluoro-1-β-L-Ribofuranosylpyrimidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.