Description

Platensimycin CAS NO 835876-32-9 is a novel, potent natural product antibiotic belonging to the class of FabF/B inhibitors. This compound matters for its unique mechanism of action, selectively targeting bacterial fatty acid synthesis, which offers a promising pathway for developing new antibacterial agents against resistant strains. It is primarily needed by pharmaceutical R&D teams and academic researchers focused on antimicrobial discovery and the study of bacterial metabolism.

Application

• Antibacterial Research & Development: A key lead compound for developing novel antibiotics targeting Gram-positive bacteria, including multi-drug resistant strains like MRSA (Methicillin-resistant *Staphylococcus aureus*).
• Biochemical Pathway Studies: Used as a selective inhibitor of the bacterial enzyme β-ketoacyl-acyl carrier protein synthase I/II (FabF/B) to study fatty acid biosynthesis in prokaryotes.
• Mechanism of Action (MoA) Investigation: Serves as a critical tool in microbiology and pharmacology to understand and validate new targets for antibacterial therapy.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard in quality control and method development for related pharmaceutical compounds.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research into bacterial resistance and novel therapeutic strategies.

Basic Information

Product Name	Platensimycin
CAS No.	835876-32-9
Molecular Formula	C24H27NO6
Molecular Weight	425.48 g/mol
Synonyms	Platensimycin; (4S,5R)-3-[(2S,5S,6R)-5-[(2S,3S,4R)-3,4-Dihydroxy-1-oxo-1,2,3,4-tetrahydro-2-naphthalenyl]-6-methyl-2-oxo-3,6-dihydro-2H-pyran-2-yl]-4,5-dihydroxy-5-methyl-2(5H)-furanone; Antibiotic SB-275833; SB 275833; (-)-Platensimycin
EINECS	Contact for details

Quality Control

Our Platensimycin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-grade research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.