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Verubulin CAS NO 827031-83-4
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CAS No.:827031-83-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Verubulin is a potent and selective small molecule inhibitor of microtubule polymerization. This compound matters for its targeted mechanism of action, which disrupts cell division and has shown significant research interest in oncology. It is primarily needed by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) focused on developing novel anti-cancer therapeutics and studying microtubule dynamics.
Application
- Pharmaceutical Research & Development: A key intermediate or active pharmaceutical ingredient (API) in preclinical and clinical-stage oncology programs.
- Anticancer Agent Development: Investigation as a potential therapeutic agent for various solid tumors and hematological malignancies due to its microtubule destabilizing activity.
- Biochemical Research: Used as a precise tool compound in cell biology to study mitosis, cytoskeleton function, and mechanisms of drug resistance.
- Combination Therapy Studies: Exploration in synergistic treatment regimens with other chemotherapeutic agents or targeted therapies.
- Mechanism of Action (MoA) Studies: Fundamental research into tubulin binding sites and the dynamics of microtubule assembly/disassembly.
Basic Information
| Product Name | Verubulin |
| CAS No. | 827031-83-4 |
| Molecular Formula | C₁₉H₂₁N₅O₂S |
| Molecular Weight | 383.47 g/mol |
| Synonyms | MPC-6827; Azixa; N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine; 4-(4-Methoxyphenyl)-5-methyl-2-(4-pyrimidinyl)-1H-imidazole; Carbendazim Impurity |
| EINECS | Contact for details |
Quality Control
Our Verubulin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities. Certificates of Analysis (COA) with full traceability are provided to ensure compliance with research-grade standards and support your regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥98.0% |
| Water Content (KF) | ≤0.5% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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