Description

Uridine, 4'-C-Azido-, 2',3'-Dibenzoate 5'-(3-Chlorobenzoate) (9Ci) is a chemically modified nucleoside derivative, specifically engineered as a key synthetic intermediate for advanced research and pharmaceutical development. This compound is of significant value for its role in nucleic acid chemistry, enabling the precise construction and labeling of oligonucleotides. It is primarily sought by research institutions and pharmaceutical R&D teams focused on developing novel therapeutics, diagnostic probes, and chemical biology tools.

Application

• Oligonucleotide Synthesis: A critical building block for the solid-phase synthesis of modified RNA and DNA strands, particularly for introducing azide functional groups for "click" chemistry.
• Antiviral & Anticancer Drug Development: Serves as a precursor in the research and synthesis of novel nucleoside analog prodrugs targeting viral polymerases or cellular replication pathways.
• Chemical Biology & Bioconjugation: The azide moiety allows for site-specific labeling and conjugation of biomolecules via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC).
• Probe and Diagnostic Agent Synthesis: Used to create fluorescently tagged or otherwise labeled nucleotide probes for genomic research, in situ hybridization, and diagnostic assays.
• Glycobiology Research: As a uridine derivative, it can be utilized in studies related to glycosylation pathways and the synthesis of glycosylated nucleosides.
• Medicinal Chemistry Intermediate: Provides a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) in nucleoside-based therapeutic candidates.

Basic Information

Product Name	Uridine, 4'-C-Azido-, 2',3'-Dibenzoate 5'-(3-Chlorobenzoate) (9Ci)
CAS No.	812647-80-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4'-Azido-2',3'-di-O-benzoyl-5'-O-(3-chlorobenzoyl)uridine; 2',3'-Di-O-benzoyl-5'-O-(3-chlorobenzoyl)-4'-azidouridine; 4'-Azidouridine derivative, 2',3',5'-tribenzoate; 5'-O-(3-Chlorobenzoyl)-2',3'-di-O-benzoyl-4'-azidouridine; Uridine, 4'-azido-, 2',3'-dibenzoate 5'-(3-chlorobenzoate); 4'-C-Azido-2',3'-O-dibenzoyl-5'-O-(3-chlorobenzoyl)uridine; 4'-Azido-2',3'-bis(benzoyloxy)-5'-[(3-chlorobenzoyl)oxy]uridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and structural integrity. Certificates of Analysis (COA) detailing lot-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep container tightly sealed in a dry environment to prevent moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.