Description

9-(tert-Butyldimethylsilyl)Oxymethyl-2-Aminofluorene is a protected derivative of 2-aminofluorene, featuring a tert-butyldimethylsilyl (TBDMS) ether group that enhances its stability and handling properties. This compound is a critical synthetic intermediate in advanced organic synthesis, particularly in the construction of complex molecules where the aminofluorene moiety is required. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Reagent: Used in multi-step synthesis for introducing the protected aminofluorene scaffold into larger molecular architectures.
• Material Science Research: Serves as a precursor for developing fluorescent dyes, molecular probes, and advanced organic electronic materials.
• Academic & Industrial R&D: Employed in research laboratories for methodological development in synthetic chemistry and catalysis studies.
• Agrochemical Synthesis: Potential intermediate in the development of new-generation crop protection agents with specific activity profiles.

Basic Information

Product Name	9-(tert-Butyldimethylsilyl)Oxymethyl-2-Aminofluorene
CAS No.	802909-18-8
Molecular Formula	C20H29NOSi
Molecular Weight	327.54 g/mol
Synonyms	2-Amino-9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]fluorene; 2-Amino-9-((tert-butyldimethylsilyloxy)methyl)fluorene; 9-((tert-Butyldimethylsilyloxy)methyl)-2-aminofluorene; 2-AF-TBDMS ether; TBDMS-protected 2-aminofluorene; 2-Aminofluorene-9-methanol TBDMS ether; NSC 760433
EINECS	Contact for details

Quality Control

Our production of 9-(tert-Butyldimethylsilyl)Oxymethyl-2-Aminofluorene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.