Description

Tetramethylammonium Guanosine 5'-Monophosphate is a high-purity nucleotide salt, specifically the tetramethylammonium salt of guanosine monophosphate. This compound is a critical reagent and building block in advanced biochemical research and pharmaceutical development, offering superior solubility and stability in specific formulations. It is primarily utilized by research institutions and manufacturers in the fields of nucleic acid chemistry, oligonucleotide synthesis, and as a reference standard for analytical methods.

Application

• Biochemical Research: Essential as a substrate or intermediate in enzymatic studies and metabolic pathway investigations.
• Oligonucleotide Synthesis: Serves as a protected nucleotide precursor in the solid-phase synthesis of DNA and RNA sequences.
• Pharmaceutical Development: Used in the research and development of nucleotide-based therapeutics, including antivirals and mRNA vaccines.
• Analytical Reference Standard: Employed as a high-purity standard for HPLC, LC-MS, and other chromatographic methods to quantify nucleotides.
• Enzyme Kinetics: Acts as a cofactor or inhibitor in studies of kinase and phosphorylase enzyme activities.
• Cell Culture Media: A component in specialized cell culture formulations for studying nucleotide metabolism.

Basic Information

Product Name	Tetramethylammonium Guanosine 5'-Monophosphate
CAS No.	89999-10-0
Molecular Formula	C14H26N7O8P
Molecular Weight	451.38 g/mol
Synonyms	GMP Tetramethylammonium Salt; Guanosine 5'-Monophosphate Tetramethylammonium Salt; 5'-GMP Tetramethylammonium Salt; Tetramethylammonium 5'-Guanylate; N,N,N-Trimethylmethanaminium Guanosine 5'-Monophosphate; Guanylic Acid Tetramethylammonium Salt; GMP-TMA
EINECS	Contact for details

Quality Control

Our Tetramethylammonium Guanosine 5'-Monophosphate is manufactured under strict quality systems to ensure batch-to-batch consistency for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to in-house specifications designed to meet the rigorous demands of pharmaceutical and analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
pH (1% Solution)	6.0 - 8.0
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.