Description

(2-Fluorobiphenyl-5-Yl)Methanol is a high-purity fluorinated biphenyl derivative, serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorinated aromatic system and a hydroxymethyl functional group, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used as a precursor in the synthesis of advanced herbicides, fungicides, and plant growth regulators, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated mesogens and charge-transport materials used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs), leveraging its rigid biphenyl backbone.
• Polymer Modification: Acts as a monomer or cross-linking agent for engineering polymers with enhanced thermal stability, chemical resistance, and specific optical properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and fluorination chemistry research.

Basic Information

Product Name	(2-Fluorobiphenyl-5-Yl)Methanol
CAS No.	89951-76-8
Molecular Formula	C₁₃H₁₁FO
Molecular Weight	202.22 g/mol
Synonyms	5-(Hydroxymethyl)-2-fluorobiphenyl; [1,1'-Biphenyl]-5-methanol, 2'-fluoro-; 2'-Fluoro[1,1'-biphenyl]-5-methanol; (2-Fluoro-5-biphenylyl)methanol; 2-Fluorobiphenyl-5-carbinol; 2-Fluoro-5-(hydroxymethyl)biphenyl; 2'-Fluoro-5-hydroxymethylbiphenyl
EINECS	Contact for details

Quality Control

Our (2-Fluorobiphenyl-5-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.