Description

8-Oxabicyclo[5.1.0]Octane-1-Carbonyl Chloride, cis- (9Ci) is a specialized, high-purity organic intermediate featuring a strained bicyclic epoxide structure with a reactive acid chloride functional group. This compound is critical for introducing the 8-oxabicyclo[5.1.0]octane moiety into target molecules, enabling the synthesis of complex, three-dimensional architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those requiring strained ring systems for enhanced biological activity or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored thermal or mechanical properties.
• Chemical Biology Probe Development: Employed to create molecular probes for studying enzyme mechanisms or protein-ligand interactions due to its reactive handle and rigid scaffold.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis, particularly in ring-opening and cross-coupling reactions of strained heterocycles.

Basic Information

Product Name	8-Oxabicyclo[5.1.0]Octane-1-Carbonyl Chloride, cis- (9Ci)
CAS No.	89848-85-1
Molecular Formula	C8H9ClO2
Molecular Weight	172.61 g/mol
Synonyms	cis-8-Oxabicyclo[5.1.0]octane-1-carbonyl chloride; cis-1-(Chlorocarbonyl)-8-oxabicyclo[5.1.0]octane; 1-Oxaspiro[2.6]nonane-1-carbonyl chloride, 4,5-epoxy- (related structure); Bicyclo[5.1.0]octane-1-carbonyl chloride, 8-oxa-, cis-; Epoxycycloheptanecarbonyl chloride; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Every batch of 8-Oxabicyclo[5.1.0]Octane-1-Carbonyl Chloride, cis- (9Ci) is manufactured and analyzed under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.