Description

Oxiranecarbonyl Chloride, 2-Methyl-3-Phenyl-, trans- (9Ci) is a specialized chiral epoxide building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring a reactive oxirane (epoxide) ring and an acid chloride functional group, enabling precise stereoselective transformations. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, chiral ligands, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the spatial orientation of the molecule is critical for bioactivity.
• Chiral Ligand & Catalyst Development: Serves as a precursor for creating novel asymmetric catalysts and auxiliaries used in enantioselective catalysis.
• Fine Chemical Manufacturing: Employed in multi-step syntheses of complex fragrance molecules, flavors, and other high-value specialty chemicals.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, exploring new ring-opening reactions and cascade cyclizations.
• Material Science Precursor: Potential use in synthesizing monomers for specialized polymers with tailored optical or mechanical properties.

Basic Information

Product Name	Oxiranecarbonyl Chloride, 2-Methyl-3-Phenyl-, trans- (9Ci)
CAS No.	89848-84-0
Molecular Formula	C11H9ClO2
Molecular Weight	208.64 g/mol
Synonyms	trans-2-Methyl-3-phenyloxirane-2-carbonyl chloride; (2R,3S)-2-Methyl-3-phenyloxirane-2-carbonyl chloride; (2S,3R)-2-Methyl-3-phenyloxirane-2-carbonyl chloride; 2-Methyl-3-phenylglycidoyl chloride; Phenylmethyloxiranecarbonyl chloride; trans-2-Methyl-3-phenylglycidic acid chloride; Glycidic acid chloride, 2-methyl-3-phenyl-, trans-; NSC 406916
EINECS	Contact for details

Quality Control

Every batch of Oxiranecarbonyl Chloride, 2-Methyl-3-Phenyl-, trans- is produced and analyzed under strict quality protocols to ensure consistency and purity for sensitive synthetic applications. Our standard R&D Grade material is characterized by NMR, IR, and HPLC to confirm identity, stereochemical purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.