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Isopropyl Itraconazole CAS NO 89848-49-7


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CAS No.:89848-49-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Isopropyl Itraconazole is a potent triazole antifungal agent, specifically a derivative of itraconazole. This compound is valued for its enhanced formulation properties and serves as a critical intermediate in the synthesis of advanced pharmaceutical products. It is primarily utilized by manufacturers in the pharmaceutical and agrochemical industries for research, development, and production.

Application

  • Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel antifungal APIs (Active Pharmaceutical Ingredients).
  • Agrochemical Research: Investigated for potential use in developing new fungicidal agents for crop protection.
  • Chemical Synthesis: Used in organic synthesis to create more complex triazole-based molecules for biological testing.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
  • Formulation Studies: Employed in pre-formulation research to improve the solubility and bioavailability of antifungal drugs.

Basic Information

Product Name Isopropyl Itraconazole
CAS No. 89848-49-7
Molecular Formula C37H41Cl2N8O4
Molecular Weight 732.68 g/mol
Synonyms Isopropyl Itraconazole; 4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-isopropyl-1,2,4-triazol-3-one; Itraconazole Isopropyl Derivative; 2-Isopropyl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-δ²-1,2,4-triazolin-5-one
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Quality Control

Our Isopropyl Itraconazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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