Description

(20ξ,22E,24ξ)-16β,18,20-Trihydroxy-24-Methyl-27-Norcholesta-4,22-Dien-3-One is a high-purity, structurally complex steroidal compound of significant interest in advanced research and development. This compound matters as a critical synthetic intermediate or reference standard for the development of novel bioactive molecules, particularly in the pharmaceutical and life sciences sectors. It is needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on steroid chemistry, drug discovery, and metabolic pathway studies.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate or building block in the synthesis of novel steroid-based therapeutics.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in analytical laboratories.
• Biochemical Studies: Employed in academic and industrial research to study enzyme interactions, receptor binding, and metabolic pathways involving steroidal structures.
• Fine Chemical Synthesis: Acts as a precursor for the custom synthesis of more complex, specialized steroidal compounds for various applications.
• Life Science Reagents: Utilized in the formulation of specialized reagents and kits for cellular and molecular biology research.

Basic Information

Product Name	(20ξ,22E,24ξ)-16β,18,20-Trihydroxy-24-Methyl-27-Norcholesta-4,22-Dien-3-One
CAS No.	89837-99-0
Molecular Formula	C₂₇H₄₂O₄
Molecular Weight	430.63 g/mol
Synonyms	16β,18,20-Trihydroxy-24-methyl-27-norcholesta-4,22-dien-3-one; 24-Methyl-27-norcholesta-4,22-diene-3,16β,18,20-tetrol-3-one; (20E,22E,24E)-16β,18,20-Trihydroxy-24-methyl-27-norcholesta-4,22-dien-3-one; BR-6-Aldosterone intermediate; Steroid BR-6; 27-Norcholesta-4,22-diene-3,16β,18,20-tetrol-3-one, 24-methyl-; Potential aldosterone synthase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our (20ξ,22E,24ξ)-16β,18,20-Trihydroxy-24-Methyl-27-Norcholesta-4,22-Dien-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.