Description

N6-2-(4-Aminophenyl)Ethyl-Adenosine is a chemically modified adenosine derivative, a key building block in advanced pharmaceutical and biochemical research. This compound matters for its role as a versatile intermediate in the synthesis of novel adenosine receptor ligands and other bioactive molecules. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing cardiovascular, neurological, and anti-inflammatory therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel adenosine A1, A2A, and A3 receptor agonists and antagonists for drug discovery programs.
• Biochemical Research: Used as a tool compound to study adenosine receptor signaling pathways, cellular metabolism, and nucleoside transport mechanisms.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of drug candidates.
• Diagnostic Agent Development: Potential use in developing labeled probes (e.g., fluorescent or radiolabeled) for receptor binding assays and imaging studies.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex nucleoside analogs with tailored biological activities.

Basic Information

Product Name	N6-2-(4-Aminophenyl)Ethyl-Adenosine
CAS No.	89705-21-5
Molecular Formula	C18H21N7O4
Molecular Weight	399.41 g/mol
Synonyms	N6-[2-(4-Aminophenyl)ethyl]adenosine; 2-(4-Aminophenyl)ethyladenosine; Adenosine, N6-[2-(4-aminophenyl)ethyl]-; N6-(2-(4-Aminophenyl)ethyl)adenosine; 4-Aminophenethyladenosine; N6-(4-Aminophenethyl)adenosine; APNEA (common abbreviation); N6-(p-Aminophenethyl)adenosine
EINECS	Contact for details

Quality Control

Our N6-2-(4-Aminophenyl)Ethyl-Adenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.