Description

5-(Carboxy(Hydroxy)Methyl)Uridine Methyl Ester is a high-purity, modified nucleoside derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical synthetic intermediate and building block for the creation of novel nucleotide analogs and therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on antiviral drug discovery, oligonucleotide synthesis, and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Chemistry: Used in the research and development of modified RNA and DNA strands for therapeutic and diagnostic applications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and processing.
• Prodrug Development: Utilized in the design of prodrugs to improve the bioavailability and targeting of nucleotide-based therapies.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Foundation for creating labeled or tagged nucleotides used to study biological processes.

Basic Information

Product Name	5-(Carboxy(Hydroxy)Methyl)Uridine Methyl Ester
CAS No.	89665-83-8
Molecular Formula	C12H16N2O8
Molecular Weight	316.26 g/mol
Synonyms	5-Carboxymethyluridine Methyl Ester; 5-(Carboxymethyl)uridine Methyl Ester; 5-[(Methoxycarbonyl)hydroxymethyl]uridine; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(methoxycarbonylmethyl)pyrimidine-2,4-dione; Methyl 5-Carboxymethyluridine; 5-CMUM; Uridine, 5-(carboxy(hydroxy)methyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 5-(Carboxy(Hydroxy)Methyl)Uridine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when opening. For long-term storage, consider desiccant and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.