Description

3-Pyridinecarbonyl Chloride, 4-Chloro-2,6-Dimethyl- (9Ci) is a high-purity, functionalized heterocyclic acid chloride building block. This compound is critical for the synthesis of complex molecules, offering a reactive site for amide bond formation and other nucleophilic substitutions. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting nicotinic receptors or requiring functionalized pyridine cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the chlorinated dimethylpyridine structure confers specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of functional polymers and advanced organic materials with tailored properties.
• Custom Synthesis and Contract Manufacturing: An essential building block for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 4-Chloro-2,6-Dimethyl- (9Ci)
CAS No.	89662-90-8
Molecular Formula	C8H7Cl2NO
Molecular Weight	204.05 g/mol
Synonyms	4-Chloro-2,6-dimethylnicotinoyl chloride; 4-Chloro-2,6-dimethylpyridine-3-carbonyl chloride; 3-Carbonyl chloride-4-chloro-2,6-dimethylpyridine; 4-Chloro-2,6-dimethyl-3-pyridinecarbonyl chloride; 4-Chloro-2,6-dimethylnicotinic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonyl Chloride, 4-Chloro-2,6-Dimethyl- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.