Description

Carbonochloridic Acid, Tetrahydro-2H-Pyran-4-Yl Ester is a versatile and reactive chemical intermediate, primarily valued for its role in the synthesis of complex organic molecules. Its core value proposition lies in providing a protected, activated carboxylic acid derivative, enabling efficient amide and ester bond formation under mild conditions. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing tetrahydro-2H-pyran or piperidine scaffolds.
• Peptide Coupling Reagent: Used as an activating agent for carboxylic acids in peptide synthesis and other amide bond formation reactions.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and insecticides that require specific heterocyclic components.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with tailored properties.
• Organic Synthesis Reagent: Facilitates acylation reactions in academic and industrial research laboratories for the preparation of esters, carbonates, and ureas.
• Material Science Research: Used in the development of novel organic materials, liquid crystals, and functional coatings.

Basic Information

Item	Detail
Product Name	Carbonochloridic Acid, Tetrahydro-2H-Pyran-4-Yl Ester
CAS No.	89641-80-5
Molecular Formula	C7H11ClO3
Molecular Weight	178.62 g/mol
Synonyms	Tetrahydro-2H-pyran-4-yl chloroformate; 4-Chloroformyloxytetrahydropyran; Tetrahydropyran-4-yl chloroformate; THP-Chloroformate; Oxane-4-yl carbonochloridate; 4-Pyranyl chloroformate; Chloroformic acid tetrahydro-2H-pyran-4-yl ester
EINECS	Contact for details

Quality Control

Our Carbonochloridic Acid, Tetrahydro-2H-Pyran-4-Yl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.