Description

1-Pyrrolidinecarbonyl Chloride, 2-Ethyl- (9Ci) is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the 2-ethylpyrrolidinecarbonyl moiety, a valuable structural motif for modulating the physicochemical and biological properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrrolidine ring can enhance bioavailability and target specificity.
• Peptide Mimetics & PROTACs: Facilitates the construction of peptide-like structures and proteolysis-targeting chimeras (PROTACs) for drug discovery programs.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological pathways and protein function.

Basic Information

Product Name	1-Pyrrolidinecarbonyl Chloride, 2-Ethyl- (9Ci)
CAS No.	89629-92-5
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	2-Ethylpyrrolidine-1-carbonyl chloride; 1-(Chlorocarbonyl)-2-ethylpyrrolidine; 2-Ethyl-1-pyrrolidinecarbonyl chloride; 2-Ethylpyrrolidine-1-carboxylic acid chloride; N-Carboxy-2-ethylpyrrolidine chloride; 2-Ethyl-1-pyrrolidinecarboxylic acid chloride; 2-Ethyl-pyrrolidine-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarbonyl Chloride, 2-Ethyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of our global pharmaceutical and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.