Description

Temarotene is a synthetic retinoid compound with significant pharmacological activity. This active pharmaceutical ingredient (API) is valued for its targeted therapeutic effects in dermatological and oncological research. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel treatments. Our supply ensures high purity and consistent quality for critical R&D and production needs.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of prescription dermatological medications.
• Dermatological Research: Investigation into treatments for severe acne, psoriasis, and other keratinization disorders.
• Oncology Research: Studies exploring its potential in chemoprevention and differentiation therapy for certain cancers.
• Preclinical & Clinical Development: Sourcing for toxicity studies, pharmacokinetic profiling, and clinical trial material.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Cosmeceutical R&D: Exploration in advanced anti-aging and skin-repair formulations at the research stage.

Basic Information

Product Name	Temarotene
CAS No.	89410-65-1
Molecular Formula	C23H28O2
Molecular Weight	336.47 g/mol
Synonyms	4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl]benzoic Acid; Ro 15-0778; Arotinoid Ethylester; Temarotène; Temaroteno
EINECS	Contact for details

Quality Control

Our Temarotene is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.