Description

5-((Methylamino)Methyl)-2-Selenouridine is a modified nucleoside analog where selenium replaces the oxygen atom at the 2-position of the uracil base. This compound is of significant interest in biochemical and pharmaceutical research due to its unique selenium incorporation, which can impart distinct electronic and catalytic properties. It serves as a critical building block and research tool for scientists in nucleic acid chemistry, medicinal chemistry, and molecular biology, particularly in the development of novel therapeutics and probes.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel selenium-containing nucleoside analogs for potential antiviral or anticancer agents.
• Biochemical Probes: Used to study nucleic acid structure, function, and protein-nucleic acid interactions due to the unique properties of selenium.
• Antisense & RNA Therapeutics: Investigation as a modified building block for oligonucleotide synthesis to enhance stability and biological activity.
• Enzyme Mechanism Studies: Serves as a substrate or inhibitor for enzymes involved in nucleotide metabolism and salvage pathways.
• Diagnostic Reagent Development: Potential use in the creation of specialized diagnostic kits and assays.
• Academic & Institutional Research: Fundamental research tool in chemistry and biology departments for exploring the role of modified nucleosides.

Basic Information

Product Name	5-((Methylamino)Methyl)-2-Selenouridine
CAS No.	89314-80-7
Molecular Formula	C11H17N3O5Se
Molecular Weight	366.24 g/mol
Synonyms	2-Selenouridine, 5-[(Methylamino)methyl]-; 5-(Methylaminomethyl)-2-selenouridine; 5-[(Methylamino)methyl]-2-selenouridine; 2-Seleno-5-[(methylamino)methyl]uridine; 5-(N-Methylaminomethyl)-2-selenouridine; Se2Urd derivative; Selenium-modified uridine
EINECS	Contact for details

Quality Control

Our 5-((Methylamino)Methyl)-2-Selenouridine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for research and pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.