Description

2-Thiophenecarboxylicacid,5-(Chloroformyl)-(7Ci) is a high-value, reactive heterocyclic building block used in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and functional materials, enabling the introduction of the thiophene moiety with a reactive acid chloride handle. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or coupling agent in the development of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Research & Development: Essential for academic and industrial research laboratories exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2-Thiophenecarboxylicacid,5-(Chloroformyl)-(7Ci)
CAS No.	89284-70-8
Molecular Formula	C6H3ClO2S
Molecular Weight	174.60 g/mol
Synonyms	5-(Chloroformyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-(chlorocarbonyl)-; 5-Carboxy-2-thiophenecarbonyl chloride; Thiophene-2,5-dicarboxylic acid chloride (mono-); 2,5-Thiophenedicarboxylic acid chloride; 5-Chloroformylthiophene-2-carboxylic acid; 2-Carboxythiophene-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-Thiophenecarboxylicacid,5-(Chloroformyl)-(7Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.