Description

(1β,3α,5β)-1,3-Dihydroxy-Cholan-24-Oic Acid CAS NO 89238-74-4 is a high-purity, dihydroxylated bile acid derivative, a key intermediate in the synthesis of advanced pharmaceutical compounds. Its precise stereochemistry and functional groups make it a valuable building block for developing targeted therapeutic agents. This compound is essential for research and production in the pharmaceutical and biotechnology sectors, particularly for metabolic and liver-related drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents, particularly those targeting metabolic pathways and liver function.
• Biochemical Research: Used as a reference standard and research tool in studies of bile acid metabolism, receptor interactions, and signaling pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral building block for the manufacture of complex, high-value APIs.
• Metabolic Disorder Studies: Employed in preclinical and clinical research focused on conditions related to cholesterol and lipid metabolism.
• Cell Culture & Media Supplementation: May be utilized in specialized cell culture applications to study cellular responses to specific bile acid derivatives.

Basic Information

Product Name	(1β,3α,5β)-1,3-Dihydroxy-Cholan-24-Oic Acid
CAS No.	89238-74-4
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57 g/mol
Synonyms	1β,3α-Dihydroxy-5β-cholan-24-oic Acid; 1β,3α-Dihydroxy-5β-cholanic Acid; 3α,1β-Dihydroxy-5β-cholan-24-oic Acid; 1β,3α-Dihydroxy-5β-cholanoic Acid; (1β,3α,5β)-1,3-Dihydroxycholan-24-oic Acid; 1,3-Dihydroxy-5β-cholan-24-oic Acid; 5β-Cholan-24-oic acid, 1,3-dihydroxy-, (1β,3α,5β)-
EINECS	Contact for details

Quality Control

Our (1β,3α,5β)-1,3-Dihydroxy-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.