Description

Cyclobutanecarbonyl Chloride, 2-Chloro- (7Ci) CAS NO 89182-33-2 is a highly reactive and versatile acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the sterically defined 2-chlorocyclobutanecarbonyl moiety, enabling the construction of complex molecular architectures with specific conformational properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those requiring constrained ring systems for enhanced biological activity and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclobutane ring can contribute to unique modes of action.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored thermal and mechanical properties.
• Peptide Mimetics & Conformationally Restricted Analogs: Facilitates the creation of peptide-like structures with rigidified backbones for biochemical and medicinal chemistry studies.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	Cyclobutanecarbonyl Chloride, 2-Chloro- (7Ci)
CAS No.	89182-33-2
Molecular Formula	C5H6Cl2O
Molecular Weight	153.01 g/mol
Synonyms	2-Chlorocyclobutanecarbonyl Chloride; 2-Chlorocyclobutanecarboxylic Acid Chloride; 2-Chloro-1-cyclobutanecarbonyl Chloride; (2-Chlorocyclobutyl)carbonyl Chloride; 2-Chlorocyclobutane-1-carbonyl Chloride; Cyclobutanecarbonyl chloride, 2-chloro-; 1-Cyclobutanecarbonyl chloride, 2-chloro-
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarbonyl Chloride, 2-Chloro- is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and scale-up applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Purity (GC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.