Description

1,2-Cyclopropanedicarbonyl Chloride (6Ci,7Ci) is a highly reactive and versatile bicyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique strained-ring structure and dual acyl chloride functionalities make it an invaluable precursor for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to introduce the cyclopropane moiety and create novel amide or ester linkages.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those containing constrained cyclopropane rings to modulate biological activity and metabolic stability.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides, where the cyclopropane group can enhance potency and environmental profile.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the synthesis of specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the fabrication of advanced organic materials, including liquid crystals and molecular scaffolds.
• Peptide Mimetics: Useful for incorporating rigid, three-carbon bridges into peptide backbones to create conformationally restricted analogs.

Basic Information

Product Name	1,2-Cyclopropanedicarbonyl Chloride (6Ci,7Ci)
CAS No.	89180-99-4
Molecular Formula	C5H4Cl2O2
Molecular Weight	166.99 g/mol
Synonyms	Cyclopropane-1,2-dicarbonyl dichloride; 1,2-Cyclopropanedicarboxylic acid dichloride; Bicyclo[1.1.0]butane-2,4-dicarbonyl chloride; 6Ci,7Ci; 2,4-Dichlorocarbonylbicyclo[1.1.0]butane; 1,2-Bis(chlorocarbonyl)cyclopropane
EINECS	Contact for details

Quality Control

Every batch of 1,2-Cyclopropanedicarbonyl Chloride is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, alcohols, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.