Description

Benzeneacetyl Bromide, α-Oxo- (9Ci) is a versatile and reactive acyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the α-oxo-benzeneacetyl moiety, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing α-ketoamide or related pharmacophores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the α-oxo-benzoyl group is a key structural element.
• Peptide Mimetics & Protease Inhibitors: Crucial for constructing peptide bond isosteres and inhibitors targeting various proteases.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel polymers and organic electronic materials with specific functional properties.
• Chemical Biology Probes: Useful for the site-specific labeling and modification of biomolecules in research applications.

Basic Information

Product Name	Benzeneacetyl Bromide, α-Oxo- (9Ci)
CAS No.	89177-96-8
Molecular Formula	C8H5BrO2
Molecular Weight	213.03 g/mol
Synonyms	2-Bromo-1-phenylethan-1-one; Phenacyl bromide; α-Bromoacetophenone; ω-Bromoacetophenone; Acetophenone, 2-bromo-; Benzoylmethyl bromide; (Bromoacetyl)benzene; Tocopheryl Acetate (common mis-association, included for clarity)
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetyl Bromide, α-Oxo- is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles to ensure consistency and reliability for your critical synthetic processes. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.