Description

5-Isothiazolecarbonylchloride,4-Chloro-3-Methyl-(7Ci) is a specialized heterocyclic building block and key reactive intermediate in advanced organic synthesis. Its value lies in its ability to introduce the functionalized isothiazole moiety into target molecules, enabling the development of novel compounds with specific biological or material properties. This high-purity intermediate is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by material scientists exploring functional polymers and dyes.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting neurological disorders, infectious diseases, and inflammation.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the isothiazole ring.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized heterocyclic dyes and pigments for high-performance applications.
• Chemical Biology Probes: Utilized to create labeled compounds or active site-directed inhibitors for proteomic and genomic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	5-Isothiazolecarbonylchloride,4-Chloro-3-Methyl-(7Ci)
CAS No.	89167-43-1
Molecular Formula	C5H3Cl2NOS
Molecular Weight	196.06 g/mol
Synonyms	4-Chloro-3-methyl-1,2-thiazole-5-carbonyl chloride; 4-Chloro-3-methylisothiazole-5-carbonyl chloride; 4-Chloro-3-methyl-5-isothiazolecarbonyl chloride; 3-Methyl-4-chloroisothiazole-5-carbonyl chloride; 5-Carbonylchloride-4-chloro-3-methylisothiazole; 4-Chloro-3-methyl-1,2-thiazol-5-yl carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Isothiazolecarbonylchloride,4-Chloro-3-Methyl-(7Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.