Description

4-o-Acetyl-3,6-Di-o-Benzyl-2-Deoxy-2-Phthalimido-Alpha,β-Glucopyranosyl Chloride is a sophisticated glycosyl donor intermediate of significant importance in synthetic carbohydrate chemistry. Its value lies in its role as a key building block for the stereoselective synthesis of complex oligosaccharides and glycoconjugates. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors, particularly for developing novel therapeutics, vaccines, and diagnostic agents.

Application

• Glycosylation Reactions: Acts as a crucial glycosyl donor for the synthesis of complex oligosaccharides and glycans with controlled stereochemistry.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of novel antibiotics, antiviral drugs, and anticancer agents.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and other biologically active glycoconjugates for therapeutic and diagnostic applications.
• Carbohydrate Chemistry Research: An essential reagent for academic and industrial research focused on understanding and manipulating carbohydrate-based biological processes.
• Vaccine Development: Employed in the synthesis of carbohydrate antigens for conjugate vaccine development against bacterial pathogens.
• Enzyme Substrate/Inhibitor Synthesis: Used to create substrates or inhibitors for glycosidases and glycosyltransferases, important targets in drug discovery.

Basic Information

Product Name	4-o-Acetyl-3,6-Di-o-Benzyl-2-Deoxy-2-Phthalimido-Alpha,β-Glucopyranosyl Chloride
CAS No.	89067-91-4
Molecular Formula	C30H28ClNO7
Molecular Weight	550.00 g/mol
Synonyms	2-Deoxy-2-phthalimido-3,6-di-O-benzyl-4-O-acetyl-α/β-D-glucopyranosyl chloride; 3,6-Di-O-benzyl-2-deoxy-2-phthalimido-4-O-acetyl-D-glucopyranosyl chloride; 1-Chloro-4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-α/β-D-glucopyranose; Glucosamine derivative glycosyl chloride; N-Phthaloyl-protected glucosamine glycosyl donor; Benzylated glucosyl chloride donor
EINECS	Contact for details

Quality Control

Our 4-o-Acetyl-3,6-Di-o-Benzyl-2-Deoxy-2-Phthalimido-Alpha,β-Glucopyranosyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Anomeric mixture)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.