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n-(9 β-D-2'-Deoxyribofuranosylpurin-6-Yl)Glycinamide CAS NO 89014-18-6


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CAS No.:89014-18-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(9 β-D-2'-Deoxyribofuranosylpurin-6-Yl)Glycinamide is a specialized nucleoside derivative, a modified adenine analog of significant interest in advanced biochemical research and pharmaceutical development. Its core value lies in its role as a key synthetic intermediate or building block for novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. This high-purity compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and prodrug synthesis. Precise molecular structure and purity are critical for ensuring reproducible results in sensitive biological assays and synthesis pathways.

Application

  • Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and repair mechanisms.
  • Prodrug Development: Acts as a precursor molecule for designing targeted prodrugs with enhanced bioavailability and reduced side effects.
  • Antiviral Agent Synthesis: A key starting material for research into nucleoside-based therapies targeting viral polymerases.
  • Labeled Compound Synthesis: Utilized in the preparation of isotopically labeled (e.g., C13, N15) compounds for metabolic tracing and pharmacokinetic studies.
  • Academic & Institutional Research: Fundamental tool for investigating nucleoside chemistry, structure-activity relationships (SAR), and medicinal chemistry.

Basic Information

Product Name n-(9 β-D-2'-Deoxyribofuranosylpurin-6-Yl)Glycinamide
CAS No. 89014-18-6
Molecular Formula C₁₂H₁₆N₆O₅
Molecular Weight 324.29 g/mol
Synonyms 2'-Deoxyadenosine-6-ylglycinamide; N-(9-β-D-2'-Deoxyribofuranosylpurin-6-yl)glycinamide; Glycinamide, N-(9-β-D-2'-deoxyribofuranosyl-9H-purin-6-yl)-; 6-(Glycinamido)purine 2'-deoxyriboside; 2'-Deoxy-6-glycinamidopurine riboside; Deoxyadenosine glycinamide derivative; Purine nucleoside glycinamide
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Quality Control

Our n-(9 β-D-2'-Deoxyribofuranosylpurin-6-Yl)Glycinamide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet general laboratory and fine chemical standards, specifications can be aligned with specific project requirements. We are committed to supply reliability and quality assurance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Solubility Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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