Description

trans-Retinoyl Chloromethane is a specialized retinoid derivative, a key synthetic intermediate in advanced organic synthesis. This compound is valued for its reactive chloromethane group attached to the retinoyl moiety, enabling precise chemical modifications. It is primarily utilized by research institutions and pharmaceutical developers working on novel vitamin A analogs, drug discovery programs, and the synthesis of bioactive molecules for dermatological and oncological research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel retinoid-based therapeutics and prodrugs.
• Biochemical Research: Used in studies investigating retinoid signaling pathways, receptor binding, and metabolic processes.
• Dermatological Agent Development: Serves as a precursor for compounds under investigation for treating skin conditions like acne and psoriasis.
• Chemical Biology Probes: Employed in the creation of molecular probes to study cellular differentiation and apoptosis.
• Organic Synthesis: Utilized in advanced organic reactions, including nucleophilic substitutions and cross-coupling, to construct complex molecular architectures.

Basic Information

Product Name	trans-Retinoyl Chloromethane
CAS No.	88981-45-7
Molecular Formula	C22H31ClO2
Molecular Weight	362.94 g/mol
Synonyms	Retinoyl Chloromethane; (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoyl Chloromethane; Chloromethyl Retinoate; trans-Retinyl Chloromethyl Ketone; Vitamin A Acid Chloromethyl Derivative; All-trans-Retinoyl Chloromethane
EINECS	Contact for details

Quality Control

Our trans-Retinoyl Chloromethane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.