Description

Cyclohexanecarbonyl Chloride, 4-Chloro-2-Methyl-, (1Alpha,2Beta,4Alpha)- (9Ci) is a high-purity, stereochemically defined acyl chloride derivative that serves as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and reactive carbonyl chloride group make it an indispensable intermediate for constructing complex molecules with defined three-dimensional architecture. This compound is primarily sought by R&D and process development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel therapeutic agents, particularly in developing central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where the rigid cyclohexane backbone and functional group are advantageous.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 4-Chloro-2-Methyl-, (1Alpha,2Beta,4Alpha)- (9Ci)
CAS No.	88938-98-1
Molecular Formula	C8H12Cl2O
Molecular Weight	195.09 g/mol
Synonyms	(1R,2S,4R)-4-Chloro-2-methylcyclohexanecarbonyl chloride; (1α,2β,4α)-4-Chloro-2-methylcyclohexanecarbonyl chloride; 4-Chloro-2-methylcyclohexanecarbonyl chloride, (1R,2S,4R)-; trans-4-Chloro-2-methylcyclohexanecarbonyl chloride; Cyclohexanecarbonyl chloride, 4-chloro-2-methyl-, (1R,2S,4R)-; (1R,2S,4R)-4-Chloro-2-methyl-1-cyclohexanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of our Cyclohexanecarbonyl Chloride, 4-Chloro-2-Methyl-, (1Alpha,2Beta,4Alpha)- (9Ci) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity (by GC/HPLC), chiral purity, and impurity profiles are available for each lot. Our quality protocols are designed to support regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.