Description

2(3H)-Isoxazolecarbonylchloride,5-(Chloromethyl)-3-Oxo-(9Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. This compound matters for its bifunctional reactivity, featuring both an acid chloride and a chloromethyl group, enabling sequential derivatization to construct complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel isoxazole-containing drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that leverage the isoxazole scaffold for bioactivity.
• Chemical Biology Probes: Serves as a versatile linker or reactive handle for modifying proteins, peptides, or other biomolecules in probe development.
• Material Science Research: Employed in the creation of specialized polymers or functional materials where the isoxazole ring imparts specific thermal or chemical properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in heterocyclic and multicomponent reactions.

Basic Information

Product Name	2(3H)-Isoxazolecarbonylchloride,5-(Chloromethyl)-3-Oxo-(9Ci)
CAS No.	88918-36-9
Molecular Formula	C5H3Cl2NO2
Molecular Weight	179.99 g/mol
Synonyms	5-(Chloromethyl)-3-oxo-2(3H)-isoxazolecarbonyl chloride; 5-(Chloromethyl)-3-oxoisoxazole-2-carbonyl chloride; 2(3H)-Isoxazolecarbonyl chloride, 5-(chloromethyl)-3-oxo-; 5-Chloromethyl-3-oxo-2-isoxazolecarbonyl chloride; 3-Oxo-5-chloromethylisoxazole-2-carbonyl chloride; 88918-36-9; 5-(Chloromethyl)-3-oxo-2,3-dihydroisoxazole-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of our 2(3H)-Isoxazolecarbonylchloride,5-(Chloromethyl)-3-Oxo-(9Ci) undergoes rigorous analytical testing to ensure identity, purity, and consistency suitable for research and process development. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific results and compliance with our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.