Description

Liranaftate is a synthetic allylamine antifungal agent known for its potent activity against dermatophytes and other fungi. This compound is a critical active pharmaceutical ingredient (API) valued for its efficacy in treating topical fungal infections. It is primarily utilized by pharmaceutical manufacturers in the development and production of antifungal creams, powders, and sprays for the global healthcare market.

Application

• Pharmaceutical API: Core active ingredient in prescription and over-the-counter (OTC) topical antifungal medications.
• Dermatological Creams & Ointments: Formulated into treatments for tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch).
• Antifungal Powders & Sprays: Used in formulations designed for application to skin folds and feet to prevent and treat fungal growth.
• Veterinary Antifungals: Incorporated into topical treatments for fungal skin infections in animals.
• Cosmecutical Products: Potential use in dandruff-control shampoos and products addressing mild fungal-related skin conditions.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological research for novel antifungal agents.

Basic Information

Product Name	Liranaftate
CAS No.	88678-31-3
Molecular Formula	C21H21NO3S
Molecular Weight	367.46 g/mol
Synonyms	(2E)-N-(6-Methoxy-2-pyridyl)-2-methyl-N-(3-methylphenyl)thio-2-propenamide; (E)-N-(6-Methoxy-2-pyridyl)-2-methyl-N-(3-methylphenyl)thio-2-propenamide; Liranaflate; Piritetrate; Zefnart; Liranaftatum; Liranaftato; Liranaftat
EINECS	Contact for details

Quality Control

Our Liranaftate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) confirming compliance with in-house and relevant pharmacopeial standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 1.5%
Loss on Drying	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.