Description

Trospectomycin is a semisynthetic aminoglycoside antibiotic derived from spectinomycin, known for its potent activity against a broad spectrum of Gram-positive and Gram-negative bacteria. Its primary value lies in its efficacy against pathogens resistant to other aminoglycosides, making it a critical tool in advanced antimicrobial research and development. This compound is essential for pharmaceutical R&D laboratories, academic institutions, and manufacturers focused on developing novel antibacterial agents and studying bacterial resistance mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of advanced antibiotic formulations and novel antimicrobial compounds.
• Antimicrobial Research: Used in microbiological and biochemical research to study bacterial protein synthesis inhibition, mechanisms of action, and the development of antibiotic resistance.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and assay of related pharmaceutical products.
• Veterinary Medicine Development: Investigated for potential applications in developing treatments for bacterial infections in animals.
• Mechanistic Studies: A valuable tool for studying the structure-activity relationships (SAR) of aminoglycoside antibiotics to guide the design of next-generation drugs.

Basic Information

Product Name	Trospectomycin
CAS No.	88669-04-9
Molecular Formula	C₂₂H₄₃N₅O₁₀
Molecular Weight	561.61 g/mol
Synonyms	U-63366F; Trospectomycin Sulfate (common salt form); (2R,4aR,5aR,7S,9S,10aR,11aS)-7,9-Diamino-2-[[(2S,5R)-5-(dimethylamino)tetrahydro-2-furanyl]oxy]decahydro-4a,7,9-trihydroxy-6-methyl-4H-pyrano[2,3-b][1,4]benzodioxin-4-one; 4'-Deoxy-4'-(2-aminoethyl)amino-4'-epispectinomycin; Antibiotic U-63366F
EINECS	Contact for details

Quality Control

Our Trospectomycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.