Description

2,4,5-Trifluorobenzoyl Chloride is a high-purity fluorinated aromatic acid chloride serving as a critical building block in advanced organic synthesis. Its value lies in enabling the efficient introduction of the 2,4,5-trifluorobenzoyl moiety, a key structural motif that can enhance the potency and metabolic stability of target molecules. This intermediate is essential for research and production within the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethylbenzoyl group contributes to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Polymer Chemistry: Employed as a monomer or modifying agent to create specialty polymers with unique thermal and chemical resistance properties.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions to introduce aromatic carbonyl groups under mild conditions.
• Material Science Research: Used in developing organic semiconductors, photovoltaic materials, and other advanced electronic materials.

Basic Information

Product Name	2,4,5-Trifluorobenzoyl Chloride
CAS No.	88419-56-1
Molecular Formula	C7H2ClF3O
Molecular Weight	194.54 g/mol
Synonyms	2,4,5-Trifluorobenzoic acid chloride; Benzoyl chloride, 2,4,5-trifluoro-; 2,4,5-Trifluorobenzoyl chloride; α,2,4-Trifluorobenzoyl chloride; 2,4,5-Trifluorobenzenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.