Description

(1S)-3,4-Dihydro-3β-(2-Hydroxyethyl)-9-Hydroxy-1α-Methyl-4Aβ,10Aβ-Epoxy-1H-Naphtho[2,3-C]Pyran-5,10-Dione is a complex, high-purity organic compound belonging to the naphthopyranone class, valued for its specific stereochemistry and functional groups. This compound is critical for advanced research and development, particularly in pharmaceutical chemistry where precise molecular architecture is paramount. It serves as a sophisticated key intermediate or reference standard for scientists in medicinal chemistry, process development, and analytical laboratories requiring materials of exacting purity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for complex target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Chemistry Development: Acts as a reference point or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Analytical Reference Standard: Provides a high-purity benchmark for quality control, method development, and validation in HPLC, LC-MS, and NMR analyses.
• Academic & Institutional Research: Supports cutting-edge organic synthesis and chemical biology studies in universities and research institutes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for CDMOs (Contract Development and Manufacturing Organizations) specializing in complex, multi-step syntheses.

Basic Information

Product Name	(1S)-3,4-Dihydro-3β-(2-Hydroxyethyl)-9-Hydroxy-1α-Methyl-4Aβ,10Aβ-Epoxy-1H-Naphtho[2,3-C]Pyran-5,10-Dione
CAS No.	88293-11-2
Molecular Formula	C₁₉H₂₀O₇
Molecular Weight	360.36 g/mol
Synonyms	9-Hydroxy-1α-methyl-4aβ,10aβ-epoxy-3β-(2-hydroxyethyl)-3,4-dihydro-1H-naphtho[2,3-c]pyran-5,10-dione; (1S)-3,4-Dihydro-3β-(2-hydroxyethyl)-9-hydroxy-1α-methyl-4aβ,10aβ-epoxy-1H-naphtho[2,3-c]pyran-5,10-dione; 1H-Naphtho[2,3-c]pyran-5,10-dione, 3,4-dihydro-3β-(2-hydroxyethyl)-9-hydroxy-1α-methyl-4aβ,10aβ-epoxy-, (1S)-; CAS 88293-11-2
EINECS	Contact for details

Quality Control

Every batch of our (1S)-3,4-Dihydro-3β-(2-Hydroxyethyl)-9-Hydroxy-1α-Methyl-4Aβ,10Aβ-Epoxy-1H-Naphtho[2,3-C]Pyran-5,10-Dione undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality systems are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.